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LIVE VIRTUAL WEBINAR: Factor X: From Thrombokinase to Oral Anticoagulants and Beyond

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Add to Calendar LIVE VIRTUAL WEBINAR: Factor X: From Thrombokinase to Oral Anticoagulants and Beyond 11/6/2020 8:00:00 AM 11/6/2020 4:30:00 PM America/New_York For More Details: https://yale.cloud-cme.com/course/courseoverview?EID=13500 Description: 75 Years of Discovery Focused on Coagulation Factor X-Thrombokinase. This one-day symposium, held live via Zoom, will include internationally recognized experts who made significant contributions to the current understanding of structure, function and medical significance of Factor X. Zoom Webinar false MM/DD/YYYY


Date & Location
Friday, November 6, 2020, 8:00 AM - 4:30 PM, Zoom Webinar

Target Audience
Specialties - Multiple Specialties

Overview

75 Years of Discovery Focused on Coagulation Factor X-Thrombokinase. This one-day symposium, held live via Zoom, will include internationally recognized experts who made significant contributions to the current understanding of structure, function and medical significance of Factor X.


Objectives
  1. Review the central role of Factor Xa in the coagulation process
  2. Appreciate the complexity of Factor Xa activities and co-factor interaction
  3. Discuss how Factor Xa became the focus of anticoagulant therapy
  4. Explore the discovery of non-enzymatic properties of Factor X

Registration
Registration fees:
  • Registration (no CME credit) - complimentary, online registration required
  • General Registration (CME credit included) - $25
  • Residents/Fellows/Students - complimentary, online registration required
  • Full-time Yale Faculty - complimentary, online registration required

*All cancellations must be received in writing (or via e-mail) at least one week prior to the start of the conference to receive a refund. Any requests for refunds received after this date, or by telephone, will not be honored.

†A letter of verification from department head must accompany registration. Letter should be sent separately to Yale CME at the address below. You may also e-mail a pdf copy of your verification letter to [email protected]. 

 

Center for Continuing Medical Education
Yale School of Medicine
333 Cedar Street
Box 208052
New Haven, CT 06520-8052

*Online registration will close the afternoon before the program. Onsite registrants accepted.


Accreditation

Accreditation Statement

The Yale School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. 

Designation Statement

The Yale School of Medicine designates this live activity for a maximum of 7.0 AMA PRA Category 1 Credits(TM). Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

Disclosure Policy

It is the policy of Yale School of Medicine, Continuing Medical Education, to ensure balance, independence, objectivity and scientific rigor in all its educational programs.  All faculty participating as speakers in these programs are required to disclose any relevant financial relationship(s) they (or spouse or partner) have with a commercial interest that benefits the individual in any financial amount that has occurred within the past 12 months; and the opportunity to affect the content of CME about the products or services of the commercial interests.  The Center for Continuing Medical Education will ensure that any conflicts of interest are resolved before the educational activity occurs.


Credits
AMA PRA Category 1 Credits™ (7.00 hours), Non-Physician Attendance (7.00 hours)
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COURSE DIRECTOR

Leonard Milstone MD
Professor Emeritus of and Senior Research Scientist in Dermatology
Yale School of Medicine
New Haven, Connecticut




Member Information
Role in activity
Nature of Relationship(s) / Name of Ineligible Company(s)
Faculty Photos
Leonard Milstone, MD
Professor Emeritus of and Senior Research Scientist in Dermatology
Yale School of Medicine
New Haven, CT
Course Director, Faculty
Nothing to disclose
Faculty Photos
Richard C. Becker, MD
Professor of Medicine
University of Cincinnati College of Medicine
Cincinnati, OH
Faculty
Consulting Fee-Membership on advisory committees or review panels-Portola Pharmaceuticals, Inc.|Consulting Fee-Membership on advisory committees or review panels-Bayer Corporation|Consulting Fee-Membership on advisory committees or review panels-Janssen|Honoraria-Speaking-Medtronic, Inc.|Consulting Fee-Membership on advisory committees or review panels-Ackea
Faculty Photos
Rodney M. Camire, PhD
Professor of Pediatrics
University of Pennsylvania School of Medicine
Philadelphia, PA
Faculty
Research Grant to CHOP-Research-Pfizer, Inc.|Consulting Fee-Consulting-Pfizer, Inc.|Royalty-Inventor-Pfizer, Inc.|Sponsored Research-Research Grant to CHOP-Bayer Corporation|Consulting Fee-Membership on advisory committees or review panels-Spark Therapeutics
Faculty Photos
Craig Jackson, PhD
Visiting Professor, Department of Biochemistry
University of Hawaii
San Diego, CA
Faculty
Member-Membership on advisory committees or review panels-Biomedical Research Institute of Southern California
Faculty Photos
Robert Knabb, PhD
Consultant
Bristol Myers Squibb
Faculty
Consulting Fee-Consulting-Bristol-Myers Squibb
Faculty Photos
Kenneth G. Mann, PhD
Professor, Emeritus, Departments of Biochemistry and Medicine
University of Vermont, College of Medicine
Burlington, VT
Faculty
Consulting Fee-Consulting-Stago|Consulting Fee-Consulting-Baxalta/Shire|Stock-Stock owner-Novo Nordisk|Stock-Stock owner-Catalyst|Stock-Stock owner-Baxter International, Inc.|Stock-Stock owner-Alnylam|Stock-Stock owner-Allergan|Ownership Interest-Owner (sold October 2019)-Haematologic Technologies (sold October 2019)|Consulting Fee-Consulting-Alnylam Pharmaceuticals
Faculty Photos
Wolfram Ruf, MD
Professor of Immunology and Microbiology
The Scripps Research Institute
La Jolla, CA
Faculty
Advisory Board-Honorarium-ICONIC Therapeutics|Consulting Fee-Honorarium-ARCA biopharma
Faculty Photos
Ruth Wexler, PhD
Vice President
Bristol Myers Squibb
Faculty
Salary-Employment-Bristol-Myers Squibb

Friday, November 6, 2020

Conference Welcome and Introductions - Leonard Milstone MD - Conference Chair
8:00AM - 8:05AM
Welcome from Nancy Brown MD - Dean, Yale School of Medicine
8:05AM - 8:10AM
Enzymology of FactorXa: Thrombokinase from Paul Morawitz to JH Milstone
8:10AM - 9:00AM
Leonard Milstone, MD
Structure & Function of Factor X: Properties, Activation and Activity in Prothrombinase
9:00AM - 10:15AM
Craig Jackson, PhD
Functional Modulation: How Blood Does and Does Not Clot
10:15AM - 11:00AM
Kenneth G. Mann, PhD
Non-canonical Functions of Factor X: Pro-inflammatory and Signaling Properties
11:00AM - 12:00PM
Wolfram Ruf, MD
Panel Discussion
12:00PM - 12:30PM
Break
12:30PM - 12:55PM
Afternoon Welcome - Brian Smith MD - Deputy Dean for Clinical and Translational Research, Yale School of Medicine
12:55PM - 1:00PM
Functional Mutants of Factor X: Inherited Disease and Engineered Therapeutics
1:00PM - 2:00PM
Rodney M. Camire, PhD
From Basic Science to Life-saving Therapy: The Rationale, and Drug Discovery Efforts that Led to the Direct Factor Xa Inhibitor Eliquis
2:00PM - 3:00PM
Robert Knabb, PhD
Ruth Wexler, PhD
Oral Factor Xa Inhibitors: Critical Considerations in Clinical Development and Testing
3:00PM - 4:00PM
Richard C. Becker, MD
Panel Discussion
4:00PM - 4:30PM

DISCLOSURE FORM

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