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Severe Asthma 2018: Advances in Pathogenesis and Treatment

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Add to Calendar Severe Asthma 2018: Advances in Pathogenesis and Treatment 10/19/2018 7:00:00 AM 10/19/2018 3:00:00 PM America/New_York For More Details: https://yale.cloud-cme.com/course/courseoverview?EID=4966 Description: Asthma affects over 300 million individuals worldwide, and between 5-10% of Americans, making it one of the most prevalent common chronic diseases. Insight into medical biology provides insight into disease mechanisms. As such, asthma research is shifting from a broad perspective to a narrower focus that includes cellular profiles, protein analysis and genetic markers combined with clinical measures. Thi... The Anlyan Center for Medical Research and Education false MM/DD/YYYY


Date & Location
Friday, October 19, 2018, 7:00 AM - 3:00 PM, The Anlyan Center for Medical Research and Education

Target Audience
Specialties - Critical Care Medicine, Family Practice, General Practice, Infectious Diseases, Internal Medicine, Otolaryngology, Pediatrics

Overview
Asthma affects over 300 million individuals worldwide, and between 5-10% of Americans, making it one of the most prevalent common chronic diseases. Insight into medical biology provides insight into disease mechanisms. As such, asthma research is shifting from a broad perspective to a narrower focus that includes cellular profiles, protein analysis and genetic markers combined with clinical measures. This symposium will address underlying pathophysiology of asthma, current issues related to heterogeneity and novel therapies.

Objectives
  1. Explain how the asthmatic airway epithelium contributes to disease
  2. Recognize different inflammatory pathways by which asthma develops and identify in those pathways therapeutic targets in use or in development
  3. Discuss the heterogeneity in asthmatic patients and illustrate how to use various biomarkers to begin to personalize therapy

Registration

Registration fee* includes continental breakfast, refreshment break, and lunch:

  • Physicians – $150
  • Nurses/PAs/Allied Health Professionals – $100
  • Residents/Fellows/Students† – Complimentary, registration required
  • Exhibitors - $2,000

*All cancellations must be received in writing (or via e-mail) at least one week prior to the start of the conference to receive a refund. Any requests for refunds received after this date, or by telephone, will not be honored.

†A letter of verification from department head must accompany registration. Letter should be sent separately to Yale CME at the address below. You may also e-mail a pdf copy of your verification letter to [email protected]. 

If paying via check, include conference name in the memo, make check payable to Yale University and send to:

Center for Continuing Medical Education
Yale School of Medicine
333 Cedar Street
PO Box 208052
New Haven, CT 06520-8052

*Online registration will close the afternoon before the program. Onsite registrants accepted.


Accreditation

Accreditation Statement

The Yale School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. 

Designation Statement

The Yale School of Medicine designates this live activity for a maximum of 5.5 AMA PRA Category 1 Credits(TM). Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

Disclosure Policy

It is the policy of Yale School of Medicine, Continuing Medical Education, to ensure balance, independence, objectivity and scientific rigor in all its educational programs.  All faculty participating as speakers in these programs are required to disclose any relevant financial relationship(s) they (or spouse or partner) have with a commercial interest that benefits the individual in any financial amount that has occurred within the past 12 months; and the opportunity to affect the content of CME about the products or services of the commercial interests.  The Center for Continuing Medical Education will ensure that any conflicts of interest are resolved before the educational activity occurs.


Additional Information

Directions

This conference will be held at the Anlyan Center for Medical Research and Education, 1st Floor Auditorium, 300 Cedar Street, New Haven, CT.

From I-95 North or South: Leave I-95 at Exit 47 (Downtown New Haven/Rte 34). This puts you onto an exit expressway. Merge onto CT-34 W via Exit 1 toward Downtown New Haven. Follow the short expressway, and merge into the left lane after the traffic light; the entrance to the parking garage will be on your left. Visitor parking available in Air Rights Garage (see parking information below) or use the Howard Avenue Garage (see below).

From I-91 South: Leave I-91 South at Exit 1 (Downtown New Haven/Rte 34). This exit puts you onto a short expressway. Follow the short expressway, and merge into the left lane after the traffic light; the entrance to the garage will be on your left. Visitor parking available in the Air Rights Garage (see parking information below) or use the Howard Avenue Garage (see below).

Parking Information 

The Air Rights Garage is open 24 hours a day and located between North and South Frontage roads, straddling York St. Rates: 0-3 hours - $3 per hour, 4-10 hours - $12 flat rate, 10-24 hours - $18 flat rate. Walking from the garage, head southwest on York Street toward Cedar Street, for approximately 80 feet. Turn left onto Cedar Street. Continue down Cedar Street until you arrive at the intersection of Congress Avenue and Cedar Street. The Anlyan Center will be across the street.

Howard Avenue Garage, 800 Howard Ave, New Haven, CT 06519, opposite from Yale-New Haven Hospital and next to the Yale Physicians Building. The garage is located in between the streets of Davenport and Congress. It is open from 6 am to 9 pm during week days only. Rates: $3 per hour. Walking from the garage, head south toward Congress Avenue for approximately 300 feet. Turn left onto Congress Avenue and continue walking until you arrive at the intersection of Congress Avenue and Cedar Street. The Anlyan Center is located at this intersection.

The New Haven Parking Authority, (203) 946-8936, can provide further assistance for rate information.


Credits
AMA PRA Category 1 Credits™ (5.50 hours), Non-Physician Attendance (5.50 hours)

COURSE DIRECTOR
Lauren E Cohn MD
Associate Professor of Medicine 
Section of Pulmonary, Critical Care and Sleep Medicine
Co-Director, Yale Center for Asthma and Airways Disease (YCAAD)
Yale School of Medicine

Member Information
Role in activity
Nature of Relationship(s) / Name of Ineligible Company(s)
William Busse, MD
Professor of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine
University of Wisconsin
Madison, WI
Faculty
Consulting Fee-Consulting-3M|Consulting Fee-Consulting-Novartis|Consulting Fee-Consulting-AstraZeneca|Consulting Fee-Consulting-Genentech, Inc.|Consulting Fee-Consulting-Sanofi-Regeneron|Consulting Fee-Consulting-GlaxoSmithKline|Data Monitoring Board-Data Monitoring Board-Boston Scientific Corporation|Data Monitoring Board-Data Monitoring Board-Genentech, Inc.|Study Oversight Committee-Study Oversight Committee-ICON Clinical Research Ltd.
Bartolome R Celli, MD, FCCP
Professor of Medicine
Harvard Medical School
Wellesley Hills, MA
Faculty
Geoffrey L Chupp, MD
Professor of Medicine (Pulmonary); Director, Yale Center for Asthma and Airways Disease (YCAAD); Director, Pulmonary Function Laboratory, YNHH
Yale School of Medicine
Guilford, CT
Faculty
Clinical Trials-GSK, Genentech, AZ, Sanofi-Aventis, Boston Scientific, BI|Speakers Bureau-Speaking-Genentech, AZ, BI, Circassia, Teva, and GSK|IP-Composition of matter patent for and Anti-YKL-40 biologic for the treatment of severe asthma (Chupp, Cohn)
Lauren E Cohn, MD
Associate Professor of Medicine (Pulmonary)
Yale School of Medicine
New Haven, CT
Faculty
Speakers Bureau-Independent contractor (including contracted research)-AstraZeneca
Steve N Georas, MD
Professor of Medicine, Environmental Medicine. Microbiology and Immunology
University of Rochester
Rochester, NY
Faculty
Nothing to disclose
Jose L Gomez Villalobos, MD
Assistant Professor of Medicine (Pulmonary)
Yale School of Medicine
ORANGE, CT
Faculty
Consulting Fee-Consulting-IDbyDNA
Bart Lambrecht, MD
Professor of Pulmonary Medicine
University of Ghent, Belgium
Faculty
Nothing to disclose
Anuradha Ray, PhD
Professor, Department of Immunology
University of Pittsburgh School of Medicine
Philadelphia, PA
Faculty
Nothing to disclose
Carla Rothlin, PhD
Associate Professor of Immunobiology, Associate Professor of Pharmacology
Yale School of Medicine
New Haven, CT
Faculty
Honoraria-Board membership-Surface Oncology
Sanjay Sethi, MD
University at Buffalo, SUNY
Buffalo, NY
Faculty
Donata Vercelli
Professor of Cellular and Molecular Medicine, the Associate Director of the Arizona Respiratory Center, and the Director of the Arizona Center for the Biology of Complex Diseases (ABCD)
University of Arizona
Tucson, AZ
Faculty
Nothing to disclose
Julie Wang, MD
Icahn School of Medicine at Mount Sinai
New York,
Faculty
Consulting Fee-Consulting-Aimmune, DBV Technologies, ALK Abello

Friday, October 19, 2018

Registration and Continental Breakfast
7:00AM - 8:00AM
Welcome and Introductions
8:00AM - 8:15AM
Lauren E Cohn, MD
Breaking Barriers: Mechanisms and Consequences of Epithelial Barrier Dysfunction in Asthma
8:15AM - 8:45AM
Steve N Georas, MD
TYRO3 Receptor Tyrosine Kinase is a negative regulator to Type 2 Immunity
8:45AM - 9:15AM
Carla Rothlin, PhD
Parsing the Heterogeneity of Immune Responses in Severe Asthma
9:15AM - 9:45AM
Anuradha Ray, PhD
Leveraging Epigenetic Data to Understand the Asthma Trajectory
9:45AM - 10:15AM
Donata Vercelli
Refreshment Break
10:15AM - 10:30AM
A Druggable Pathway of Inflammation Induced by Charcot-Leyden Crystals in Severe Asthma
10:30AM - 11:00AM
Bart Lambrecht, MD
Asthma Exacerbations- An Achilles Heel of Treatment?
11:00AM - 11:30AM
William Busse, MD
Buffet Lunch + Non CME Lecture: Revisiting the Use of OCS in Asthma: Benefits and Risks (Supported by AstraZeneca)
11:30AM - 1:00PM
Sanjay Sethi, MD
Next Generation Biologics for Severe Asthma: Targeting the Chitinase-Like-Molecule YKL-40
1:00PM - 1:30PM
Geoffrey L Chupp, MD
Severe Asthma Subgroups with High YKL-40
1:30PM - 2:00PM
Jose L Gomez Villalobos, MD
Asthma-COPD Overlap: Myth or Reality?
2:00PM - 2:30PM
Bartolome R Celli, MD, FCCP
Food Allergies Have Been Increasing So Dramatically
2:30PM - 3:00PM
Julie Wang, MD
Panel Discussion
3:00PM - 3:30PM
Closing Remarks and Adjourn
3:30PM - 3:35PM
Lauren E Cohn, MD

The Yale School of Medicine, Department of Internal Medicine, Section of Pulmonary, Critical Care & Sleep Medicine is grateful to its supporters.  They are acknowledged in all conference materials.

This conference is supported by exhibit displays from the following companies:

AstraZeneca

Genentech

GlaxoSmithKline

Novartis

If you would like to exhibit at this event, please contact us at [email protected] or 203-785-4578 for more details.


2018 Asthma Symposium - Post Test
Post-Test (Attestation)

DISCLOSURE FORM

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